RS Research Stacks
All protocols
Weight Loss

Mazdutide Protocol

Updated 5mo ago 4 min read 176+ helpful Calculator
Beginner setup

Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.

Vial strength 5 mg
Bottle format often 3 mL
BAC water 3 mL
Concentration 1.67 mg/mL

Overview

Mazdutide is a dual GLP-1 and glucagon receptor agonist. The glucagon component adds energy expenditure on top of GLP-1 appetite suppression, which is why it targets both weight loss and metabolic health.

Preparation

Reconstitute a 5 mg vial with 3 mL of bacteriostatic water (BAC) for a ~1.67 mg/mL concentration. Gently roll the vial to dissolve; do not shake.

VialBACConcentration
5 mg3 mL1.67 mg/mL

Protocol

PeriodDoseUnits (@ 1.67 mg/mL)Frequency
Weeks 1–42.5 mg (2,500 mcg)150 units (1.50 mL)1x/week
Weeks 5–8+5 mg (5,000 mcg)300 units (3.00 mL)1x/week

Cycle

Weekly injections on a consistent day. The 3 mL dilution keeps maintenance doses measurable, but 5 mg requires a 3 mL syringe. 8-week protocols use roughly 6 vials.

Was this protocol helpful?
Share via

Dosing Calculator

5 mg + 3 mL · suggested 2.5 mg
5 mg vial · 3 mL BAC
102030405060708090100
1001.00 mL
Concentration1.67 mg/mL
Selected dose2.5 mg = 150 units · split 2 × 75 u
1 unit = 0.01 mL on a U-100 syringe. Doses round to the nearest unit.