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Tirzepatide Protocol

Updated 3mo ago 4 min read 187+ helpful Calculator
Beginner setup

Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.

Vial strength 10 mg
Bottle format often 3 mL
BAC water 2 mL
Concentration 5.00 mg/mL

Overview

Tirzepatide is a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and weight management.

Preparation

Recon: 10 mg vial + 2 mL BAC (5 mg/mL).

Protocol

PeriodDoseUnits (@ 5mg/mL)Frequency
Weeks 1-42.5 mg50 u1x/week
Weeks 5-85 mg100 u1x/week
Weeks 9-127.5 mg150 u1x/week
Weeks 13-1610 mg200 u1x/week
Weeks 17-2012.5 mg250 u1x/week
Weeks 21-2415 mg300 u1x/week

Cycle

12 weeks on, 4 weeks off.

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Dosing Calculator

10 mg + 3 mL BAC · suggested 2.5 mg
10 mg vial · 3 mL BAC
102030405060708090100
750.75 mL
Concentration3.33 mg/mL
Selected dose2.5 mg = 75 units
1 unit = 0.01 mL on a U-100 syringe. Doses round to the nearest unit.