Beginner setup
Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.
Vial strength 10 mg
Bottle format often 3 mL
BAC water 3 mL
Concentration 3.33 mg/mL
Overview
CagriSema is the fixed-ratio combination of cagrilintide (amylin analog) and semaglutide (GLP-1) — the same pairing that drove headline clinical weight-loss results. Each unit of this 10 mg blend delivers 16.7 mcg of each peptide.
Preparation
Reconstitute the 10 mg vial with 3 mL of bacteriostatic water (BAC) for a ~3.33 mg/mL total (1.67 mg/mL each peptide). Refrigerate after mixing.
| Vial | BAC | Concentration |
|---|---|---|
| 10 mg | 3 mL | 3.33 mg/mL |
Protocol
| Period | Dose | Units (@ 3.33 mg/mL) | Frequency |
|---|---|---|---|
| Weeks 1–4 | 500 mcg total (250 mcg each) | 15 units (0.15 mL) | 1x/week |
| Weeks 5–8 | 1,000 mcg total (500 mcg each) | 30 units (0.30 mL) | 1x/week |
| Weeks 9–12 | 2,000 mcg total (1,000 mcg each) | 60 units (0.60 mL) | 1x/week |
| Weeks 13–16 | 3,400 mcg total (1,700 mcg each) | 102 units (1.02 mL) | 1x/week |
| Week 17+ | 4,800 mcg total (2,400 mcg each) | 144 units (1.44 mL) | 1x/week |
Cycle
16+ week titration, once weekly on a consistent day. The 2.4 mg-each target mirrors clinical trial protocols. Larger doses need a 3 mL syringe.