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Semaglutide Protocol

Updated 3mo ago 3 min read 156+ helpful Calculator
Beginner setup

Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.

Vial strength 5 mg
Bottle format often 3 mL
BAC water 2 mL
Concentration 2.50 mg/mL

Overview

Semaglutide is a GLP-1 receptor agonist widely used for weight management and glycemic control.

Preparation

Recon: 5 mg vial + 2 mL BAC (2.5 mg/mL).

Protocol

PeriodDoseUnits (@ 2.5 mg/mL)Frequency
Weeks 1-40.25 mg10 u1x/week
Weeks 5-80.5 mg20 u1x/week
Weeks 9-121 mg40 u1x/week
Weeks 13-161.7 mg68 u1x/week
Weeks 17-202.4 mg96 u1x/week

Cycle

12-16 weeks on, 4 weeks off.

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Dosing Calculator

10 mg + 3 mL BAC · suggested 250 mcg
10 mg vial · 3 mL BAC
102030405060708090100
80.08 mL
Concentration3.33 mg/mL
Selected dose0.25 mg (250 mcg) = 8 units
1 unit = 0.01 mL on a U-100 syringe. Doses round to the nearest unit.