Overview
Sermorelin is a GHRH analog that tells the pituitary to make more growth hormone — the ‘upstream’ approach compared to secretagogues like GHRP-2. Classic use is nightly subcutaneous injection to boost the natural sleep-time GH pulse.
Preparation
Reconstitute a 5 mg vial with 3 mL of bacteriostatic water (BAC) for a ~1.67 mg/mL concentration. The bigger dilution keeps small doses readable on an insulin syringe.
| Vial | BAC | Concentration |
|---|---|---|
| 5 mg | 3 mL | 1.67 mg/mL |
Protocol
| Period | Dose | Units (@ 1.67 mg/mL) | Frequency |
|---|---|---|---|
| Weeks 1–2 | 200 mcg | 12 units (0.12 mL) | Bedtime, 1x/day |
| Weeks 3–4 | 300 mcg | 18 units (0.18 mL) | Bedtime, 1x/day |
| Weeks 5–6 | 400 mcg | 24 units (0.24 mL) | Bedtime, 1x/day |
| Weeks 7–8 | 500 mcg | 30 units (0.30 mL) | Bedtime, 1x/day |
Cycle
8–12 week cycles. Bedtime dosing matters — GH secretion peaks during sleep and Sermorelin amplifies that pulse. Adjust up slowly based on IGF-1 response.