Beginner setup
Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.
Vial strength 5 mg
Bottle format often 3 mL
BAC water 3 mL
Concentration 1.67 mg/mL
Overview
Semax is an ACTH(4-10) fragment analog developed in Russia, used as a nootropic for focus, memory, and cognitive endurance. Human trials used intranasal delivery; subcutaneous injection is the standard research route.
Preparation
Reconstitute a 5 mg vial with 3 mL of bacteriostatic water (BAC) for a ~1.67 mg/mL concentration. Refrigerate after mixing. (Intranasal protocols use a 0.5–1 mg/mL nasal spray.)
| Vial | BAC | Concentration |
|---|---|---|
| 5 mg | 3 mL | 1.67 mg/mL |
Protocol
| Period | Dose | Units (@ 1.67 mg/mL) | Frequency |
|---|---|---|---|
| Weeks 1–2 | 400 mcg (0.4 mg) | 24 units (0.24 mL) | 1x/day |
| Weeks 3–4 | 600 mcg (0.6 mg) | 36 units (0.36 mL) | 1x/day |
| Weeks 5–8 | 800 mcg (0.8 mg) | 48 units (0.48 mL) | 1x/day |
Cycle
4–8 week cycles. Morning dosing suits its stimulant-adjacent profile — it’s noticeably activating for some users.