Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.
Overview
PT-141 (bremelanotide) is a melanocortin receptor agonist that drives sexual arousal through the brain — no vascular mechanism like a PDE5 inhibitor. The FDA-approved on-demand dose is 1.75 mg SC; research protocols titrate lower.
Preparation
Reconstitute a 10 mg vial with 3 mL of bacteriostatic water (BAC) for a ~3.33 mg/mL concentration. Refrigerate after mixing — good for about 30 days.
| Vial | BAC | Concentration |
|---|---|---|
| 10 mg | 3 mL | 3.33 mg/mL |
Protocol
| Period | Dose | Units (@ 3.33 mg/mL) | Frequency |
|---|---|---|---|
| Weeks 1–8 | 500 mcg (0.5 mg) | 15 units (0.15 mL) | 1x/day |
| Weeks 9–12 | 1,000 mcg (1.0 mg) | 30 units (0.30 mL) | 1x/day |
| Weeks 13–16 | 1,500 mcg (1.5 mg) | 45 units (0.45 mL) | 1x/day |
Cycle
Up to 16-week titrations for daily protocols. For on-demand use, the approved single 1.75 mg dose before activity is the reference. Nausea is the dose-limiting side effect — start low.