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Sexual Health / Fertility

HCG Protocol

Updated 1mo ago 4 min read 341+ helpful Calculator
Beginner setup

Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.

Vial strength 10 mg
Bottle format often 3 mL
BAC water 2 mL
Concentration 5.00 mg/mL

Overview

HCG mimics LH, directly stimulating the testes to produce testosterone. It’s the standard tool for keeping testicular function alive during TRT and restarting it after a cycle. Dosed in IU, so the unit math is different from mg-based peptides.

Preparation

Reconstitute a 5,000 IU vial with 2 mL of bacteriostatic water (BAC) for a 2,500 IU/mL concentration. At this concentration, 1 unit on an insulin syringe = 25 IU. Refrigerate after mixing.

VialBACConcentration
10 mg2 mL5 mg/mL

Protocol

PeriodDoseUnits (@ 5 mg/mL)Frequency
Weeks 1–12500 IU20 units (0.20 mL)3x/week (Mon/Wed/Fri)
Short blast (Weeks 1–4)1,500–2,000 IU60–80 units (0.60–0.80 mL)3x/week
PCT taper (Weeks 1–12)1,500 → 2,000 → 1,000 IU60 → 80 → 40 units3x/week

Cycle

Maintenance: 500 IU 3x/week throughout TRT. Post-cycle: 2,000 IU 3x/week for 3 weeks, then taper. 12-week protocols are common.

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Dosing Calculator

10 mg + 2 mL · suggested 1 mg
10 mg vial · 2 mL BAC
102030405060708090100
50.05 mL
Concentration5.00 mg/mL
Selected dose0.25 mg (250 mcg) = 5 units
1 unit = 0.01 mL on a U-100 syringe. Doses round to the nearest unit.