Beginner setup
Vial sizes vary by vendor. Smaller bottles are usually 3 mL; larger bottles are often 10 mL. Match the label on the vial you actually bought, then use the calculator below if you need to adjust.
Vial strength 10 mg
Bottle format often 3 mL
BAC water 3 mL
Concentration 3.33 mg/mL
Overview
FOXO4-DRI is a senolytic peptide that selectively targets senescent (‘zombie’) cells and pushes them into apoptosis. It’s one of the most talked-about longevity peptides — and the dosing is delicate: tiny amounts, extended cycles.
Preparation
Reconstitute a 10 mg vial with 3 mL of bacteriostatic water (BAC) for a ~3.33 mg/mL concentration. Refrigerate after mixing.
| Vial | BAC | Concentration |
|---|---|---|
| 10 mg | 3 mL | 3.33 mg/mL |
Protocol
| Period | Dose | Units (@ 3.33 mg/mL) | Frequency |
|---|---|---|---|
| Weeks 1–4 | 250 mcg (0.25 mg) | 7.5 units (0.075 mL) | 1x/day |
| Weeks 5–8 | 375 mcg (0.375 mg) | 11 units (0.11 mL) | 1x/day |
| Weeks 9–16 | 500 mcg (0.5 mg) | 15 units (0.15 mL) | 1x/day |
Cycle
8–16 week cycles. Small doses and long cycles — the mouse studies that made FOXO4-DRI famous used a few months of treatment.